Conolidine’s analgesic results stem from its conversation with non-opioid pain pathways. As opposed to opioids, which bind to µ-opioid receptors during the central nervous system, conolidine modulates alternate molecular targets. A Science Advancements study identified that conolidine interacts Using the atypical chemokine receptor ACKR3/CXCR7, which regulates opioid peptide availabil... https://connerohync.blogdal.com/38249682/the-best-side-of-alternative-natural-pain-relief-to-replace-traditional-painkillers