Conolidine’s analgesic outcomes stem from its interaction with non-opioid pain pathways. Compared with opioids, which bind to µ-opioid receptors from the central anxious method, conolidine modulates alternate molecular targets. A Science Advances review discovered that conolidine interacts Together with the atypical chemokine receptor ACKR3/CXCR7, which regulates opioid peptide availa... https://socialtechnet.com/story6375504/a-review-of-alternative-natural-pain-relief-to-replace-traditional-painkillers